Technetium-99m labelled liposomes to image experimental arthritis
نویسندگان
چکیده
منابع مشابه
Technetium-99m labelled liposomes to image experimental arthritis.
OBJECTIVES Liposomes sterically stabilised with polyethylene glycol (PEG) labelled with technetium-99m were tested for their ability to image adjuvant arthritis in a rat model. METHODS Adjuvant arthritis was induced in the ankle joint of the left hind foot by injection of Mycobacterium butyricum in Freund's incomplete adjuvant in the foot pad. Seven days later animals received the following r...
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UNLABELLED The performance of 99mTc Stealth liposomes was investigated in various rat models. METHODS Preformed polyethyleneglycol-containing liposomes with encapsulated reduced glutathione, were radiolabeled using the lipophilic 99mTc-HMPAO. The labeled liposomes were intravenously administered to rats with focal S. aureus or E. coli infection, or turpentine-induced inflammation. For compari...
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The detection of focal eosinophilic inflammation by non-invasive means may aid the diagnosis and follow-up of a variety of pulmonary pathologies. All current methods of detection involve invasive sampling, which may be contraindicated or too high-risk to be performed safely. The use of injected autologous technetium-99m (Tc-99m)-labelled eosinophils coupled to single-photon emission computed to...
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Solitary parathyroid adenomas were correctly located before surgery in 20 out of 21 cases by using 20lmTl and 99mTc in a subtraction technique. The technique was not useful in identifying hyperplastic parathyroid glands. The technique is recommended as a useful procedure before surgery for primary hyperparathyroidism.
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ژورنال
عنوان ژورنال: Annals of the Rheumatic Diseases
سال: 1997
ISSN: 0003-4967
DOI: 10.1136/ard.56.6.369